The Genomic Intelligence Workflow

From Snapshot
to Streaming

Transform static genomic data into dynamic, living health intelligence. Our continuous orchestration platform replaces point-in-time reports with adaptive, audit-ready insights that evolve with emerging evidence.

The Challenge

Why Static Systems Fail

Legacy genomic workflows produce fixed reports that become outdated as evidence evolves, creating audit gaps, regulatory exposure, and clinical risk.

Audit Collapse

Fragmented audit trails cannot reconstruct analytic workflows or evidence basis, resulting in regulatory penalties and legal exposure.

Uncertainty Mismanagement

Static reports lack confidence intervals, reversibility logic, or uncertainty flags—propagating unwarranted confidence in clinical decisions.

Interpretation Decay

Variant misclassification rates of 4-60% within two years leave patients with outdated recommendations and no path to reclassification.

Consent Fragmentation

Static consent records become orphaned from data flows, creating compliance gaps and eroding patient trust.

Multi-Modal Integration

Six Data Streams, One Living Profile

Our platform ingests and harmonizes diverse data modalities into a unified, continuously updated representation of patient health.

Genomic Sequencing

Whole genome, exome, and targeted panel outputs with variant calling and annotation

Multi-Omics Streams

Proteomics, metabolomics, transcriptomics, and epigenomics data integration

EHR Integration

Clinical histories, lab results, medications, and diagnostic codes

Wearable Telemetry

Real-time sensor data from remote monitoring and continuous glucose monitors

Environmental Data

Exposure tracking, lifestyle factors, and geographic health determinants

Clinical Updates

Longitudinal treatment responses, outcomes, and care transitions

The Pipeline

Continuous Intelligence Workflow

Six integrated stages transform raw data into actionable, audit-ready clinical intelligence.

1
Multi-Modal Capture

Data Ingestion

API-driven architecture ingests genomic sequencing, multi-omics streams, EHR data, wearable telemetry, and environmental exposures through unified, secure channels.

Automated PHI/PII detection and redaction
Real-time quality validation
Consent verification at ingestion
Cryptographic provenance tagging
2
Data Harmonization

Normalization

Standardization across modalities using global ontologies and FAIR principles, with temporal alignment and versioning for complete auditability.

Ontology mapping to global schemas
Cross-modality discrepancy handling
Integrity assurance protocols
Automated remediation workflows
3
Multi-Modal Fusion

Enrichment

OmniSynth framework synthesizes data across modalities, resolving contradictions and creating the Dynamic Data Tensor—a living representation of patient health.

Clinical timeline integration
Wearable telemetry streaming
Contradiction resolution engine
Dynamic tensor construction
4
Longitudinal Intelligence

Temporal Tracking

Time-stamped event alignment builds dynamic patient timelines with immutable lineage at every update, enabling true real-time health monitoring.

Cross-modal temporal fusion
Health trend tracking
Dynamic risk recalibration
Versioned audit trails
5
Adaptive Workflows

Scenario Updates

Automated recalibration engine triggers updates based on new evidence, clinical events, or regulatory changes—ensuring interpretations remain current.

Evidence-driven triggers
Automated output refresh
User and provider feedback loops
Compliance-driven updating
6
Actionable Insights

Intelligence Output

Living Data Tensor translates into scenario-adaptive recommendations, personalized pathways, and dynamic action cards—all fully auditable and traceable.

Context-aware clinical guidance
Personalized action pathways
Evidence-tiered recommendations
Complete audit lineage
The Difference

Static vs. Streaming Intelligence

A direct comparison of legacy genomic workflows versus our continuous orchestration approach.

Aspect
Legacy Systems
Genomic Sentinel
Data Model
Static, point-in-time reports
Living Data Tensor with continuous updates
Interpretation
Fixed at time of analysis
Longitudinal reinterpretation as evidence evolves
Audit Trail
Fragmented, often incomplete
Cryptographic chain-of-custody from ingestion to output
Uncertainty
Hidden or unlabeled
Explicit quantification with evidence tiers
Consent
Static, orphaned from data
Dynamic enforcement at every analytic event
Compliance
Manual, periodic audits
Real-time surveillance with regulatory hot-swapping
Core Innovation

The Living Data Tensor

At the heart of our platform is the Dynamic Data Tensor—a multi-dimensional, continuously updated representation of patient health that integrates genomic, clinical, environmental, and behavioral data streams.

Unlike static reports that decay with time, the Living Data Tensor evolves with each new evidence input, automatically triggering reinterpretation workflows and updating clinical recommendations in real-time.

Continuous multi-omics fusion with contradiction resolution
Temporal alignment across all data modalities
Immutable version history with cryptographic attestation
Scenario-adaptive output generation

Dynamic Data Tensor: Six modalities, one living profile

Ready to Transform Your Genomic Workflow?

Discover how continuous clinical orchestration can replace static reports with living intelligence that evolves with your patients.