Key Frameworks & Terminology
The architectural components that make our platform deterministic, auditable, and regulator-ready.
ARCS
Automated Record Compliance System
An immutable, cryptographic ledger for every analytic and communication event.
Immutable Provenance Ledger
Every action from data ingestion to clinical recommendation is permanently recorded.
SHA256 Cryptographic Hash
Each entry is cryptographically signed ensuring tamper-proof audit trails.
Fail-Closed Logic
System defaults to safe state if any compliance check fails.
Real-Time Compliance
Continuous monitoring against HIPAA, GDPR, and institutional policies.
Performance Metrics
Helios Supra-Framework
The overarching platform architecture that integrates all framework components into a unified, high-performance clinical orchestration system.
Unified Integration
Seamless coordination between all framework components for cohesive operation.
Performance Optimization
Continuous monitoring and optimization of system-wide performance metrics.
Enterprise Security
Multi-layered security architecture with defense-in-depth principles.
Orchestrating a CRISPR Clinical Trial
Design
The gRNA Design Optimization Engine accelerates design from weeks to hours, harmonizing results from ≥200 independent datasets.
Model
The V-Framework models off-target effects and simulates risk under escalation scenarios (e.g., unintended indels, bystander edits).
Translate
The Clinical Translation Feasibility Analyzer generates a 'Feasibility Score: 87.4/100,' reflecting data strength and regulatory clearance likelihood.
Govern
Every step is recorded on an immutable ARCS audit ledger with a SHA256 cryptographic hash, ensuring a regulator-ready trail.
Ready to Implement These Frameworks?
Our team can help you integrate these governance and compliance frameworks into your genomic workflows.