Second-Opinion Genomic Intelligence

From Static Reports
to Living Intelligence

Transform static genomic outputs into dynamic, continuously updated health intelligence. Our second-opinion platform replaces point-in-time interpretations with adaptive, audit-ready insights that evolve with emerging evidence.

The Problem

Why Second Opinions Matter

Legacy genomic systems suffer from three critical failure modes that compromise patient care and institutional trust. Our platform addresses each systematically.

Audit Collapse

The Breakdown of Trust

Traditional genomic systems lack immutable audit trails, creating compliance gaps and eroding institutional trust.

ARCS-Grade Audit Chains with cryptographic provenance

Uncertainty Mismanagement

Propagation of Clinical Risk

Hidden or unlabeled uncertainty in genomic reports propagates clinical risk and undermines decision-making.

Explicit quantification with evidence-tier gating

Static Interpretation Collapse

Orphaned Patient Care

Point-in-time reports orphan patient care from evolving evidence, leaving diagnoses frozen in outdated science.

Longitudinal reinterpretation with living patient signatures
Our Architecture

Five Core Primitives

The architectural foundation that transforms static genomic outputs into living intelligence.

ARCS/ARCF Audit Chains

Immutable, regulatory-grade provenance with cryptographic chain-of-custody from ingestion to output.

Evidence-Tier Quantification

Algorithmic integrity filters that suppress unvalidated claims and enforce clinical safety.

Longitudinal Reinterpretation

The Living Patient Signature - continuous updates as new evidence emerges.

Scenario-Adaptive Workflows

Dynamic, contextualized decision logic with V-Framework scenario modeling.

Dynamic Consent Enforcement

Revocable, event-linked patient agency with real-time consent dashboards.

Dual Mission

Clinical Excellence & Philanthropic Impact

Analytical Services

Comprehensive variant analysis, multi-omics integration, and risk modeling

  • Variant Reinterpretation
  • Multi-Omics Synthesis
  • Pharmacogenomic Profiling

Interpretive Services

Risk stratification, personalized action plans, and scenario-adaptive recommendations

  • Risk Stratification
  • Action Plan Generation
  • V-Framework Forecasting

Regulatory Services

Audit-ready safety, privacy compliance, and real-time regulatory hot-swapping

  • Compliance Automation
  • Audit Trail Generation
  • Regulatory Hot-Swapping
The Transformation

From Legacy to Living

Legacy

Static, point-in-time reports

Genomic Sentinel

Living Data Tensor with continuous updates

Legacy

Fragmented, incomplete audit trails

Genomic Sentinel

Cryptographic chain-of-custody from ingestion to output

Legacy

Hidden or unlabeled uncertainty

Genomic Sentinel

Explicit quantification with evidence tiers

Legacy

Static consent orphaned from data

Genomic Sentinel

Dynamic enforcement at every analytic event

Measurable Impact

Performance Metrics

100%
Audit Pass Rate
Across all deployments
40%
Diagnostic Delay Reduction
Average improvement
Zero
Regulatory Penalties
Post-implementation
70%
Manual Reinterpretation Reduction
Workflow efficiency

Ready to Transform Your Genomic Intelligence?

Experience the power of living genomic intelligence. Try our interactive analysis lab or connect with our team to discuss your specific needs.